Burning sensation in the throat after drinking white wine may be due to irritation such as ethanol, gastroesophageal reflux disease and other reasons. It is recommended to choose the drug treatment, but also need to pay more attention to the daily life aspects of the intervention. 1. The stimulation of the ingredients within the white wine: ethanol and added excipients contained within the white wine will cause irritation to the mucous membrane of the throat, resulting in a burning sensation in the throat, redness and swelling of the throat, pain, and burning sensation at the throat and other symptoms. In most cases, it can disappear in a short period of time and does not require special treatment, such as drinking more water. For more serious cases, it is recommended to use medicines such as Golden Throat Capsules and Blue Scutellaria Oral Liquid under doctor’s guidance. 2. Gastroesophageal Reflux Disease (GERD): Drinking alcohol may lead to excessive secretion of gastric acid, which may result in gastric acid reflux and irritate the mucous membrane of the esophagus, resulting in burning sensation of the throat, which may be accompanied by belching, heartburn and other symptoms. It is recommended to use omeprazole enteric-coated capsules, cimetidine tablets, rehabilitation of new liquid and other drugs treatment. After drinking alcohol burning sensation in the throat, persistent unrelieved people are recommended to go to the hospital first, clear cause of the disease and follow the doctor’s instructions to standardize the use of drugs and treatment.