Hypothyroidism refers to hypothyroidism, and patients with hypothyroid nodules caused by hypothyroidism may be treated with thyroid hormone-based medications. Thyroid nodules are abnormal proliferation of thyroid cells caused by various reasons, followed by the appearance of masses within the thyroid tissue. Most of the thyroid nodules are benign and regular follow-up is recommended; if the nodules are large and show symptoms of pressure, such as difficulty in breathing or swallowing, surgical resection is needed; if the nodules are considered malignant, they should also be surgically removed. If the nodule is considered to be malignant, surgery should also be performed. If the nodule is considered to be caused by hypothyroidism, the patient should take thyroid hormone medication such as levothyroxine sodium tablets under the guidance of the doctor to adjust his/her own hormone level, which can reduce or eliminate the symptoms of hypothyroidism-induced thyroid nodules. Patients with thyroid nodules should go to the hospital in time to clarify the cause of the nodules. If the nodules are caused by hypothyroidism, levothyroxine tablets can be taken under the guidance of a doctor.