Primary cryoglobulinemia vasculitis should pay attention to keep warm, reduce the time of standing, avoid excessive exercise, in the diet should be easy to digest, nutrient-rich food. Primary cryoglobulinemia vasculitis is caused by the action of cold globulin on the body, and is mainly manifested as skin purpura, arthralgia, and purplish skin on the extremities. Patients can appear or aggravate the symptoms of numbness and pain in the limbs or joints when they are cold, so it is necessary to avoid cold stimuli and pay attention to keep warm. To reduce the time of standing, avoid standing for a long time, do not excessive physical activity, so as not to induce purpura and other skin damage. Diet should eat more easily digestible food containing protein and vitamins, such as fish, beans, milk, cereals, eggs, and a variety of fresh vegetables and fruits, with lightness as the main focus, do not eat greasy, hard, spicy food. At the same time, patients need to actively follow the doctor’s instructions to treat the original disease.