Clinically, acute nephritis usually does not need to do renal puncture, but it is needed if it is combined with other organs or systemic symptoms, or if the symptoms are not relieved after treatment. If patients with nephritis combine with other organs or systemic symptoms, such as skin rashes and sudden joint pains, combined with nephrotic syndrome, or even acute renal failure, renal puncture should be performed immediately to determine the type of pathology for the next step of treatment. If the patient with acute nephritis does not have significant symptomatic relief after treatment, and persistent hematuria, proteinuria and hypertension still exist after 3 weeks of medication, puncture examination is also needed. In addition, if patients with acute nephritis do not recover from the decline in serum C₃ for 8 weeks, renal biopsy is also needed to clarify the type of pathology, which is more helpful for treatment and prognosis. Patients with acute nephritis should go to the hospital in time and be treated under the guidance of professional physicians.