There is no such thing as three stages of perimenopause; perimenopause is the period from the onset of ovarian decline until 1 year after menopause. It includes the transitional period of menopause and early menopause. In perimenopause due to the decrease of estrogen level, vasodilatation disorder and neuropsychiatric symptoms can occur, which are manifested as hot flashes, sweating, emotional instability, irritability, insomnia, etc., and are called menopausal syndrome. 1. Menopausal transition period: It refers to the period from 45 to 55 years old, which is the period before menopause. This is the time because the number of eggs in the ovaries has decreased and the function of secreting estrogen and progesterone has also decreased. Women may experience menstrual disorders, fatigue, insomnia, hot flashes and palpitations. Due to the decline in estrogen levels, the probability of inflammation of the female genitourinary system will also increase 2. Early menopause: When menstruation stops for more than one year, it can be recognized as menopause. At this time, the reproductive organs gradually atrophy, secretions begin to decrease, may be accompanied by upset, insomnia and other plant nervous disorders. If the symptoms significantly affect daily life, hormone supplementation therapy may be prescribed by the doctor. For perimenopausal women, it is very important to maintain a relaxed mood, which is conducive to good health and family harmony. Family members should also provide adequate companionship for perimenopausal women to facilitate their smooth transition into old age.