There is still localized swelling after fifty days of shingles treatment, at which time reapplication of medication can be therapeutic. Herpes zoster is the body of varicella zoster virus reactivation triggered by local skin blisters and severe pain as the main manifestation of the skin disease, the course of the disease is generally 2 to 3 weeks, the elderly 3 to 4 weeks. However, postherpetic neuralgia, i.e., pain that lasts for 1 month or more after herpes zoster has healed, is the most common complication of herpes zoster in clinical practice. The patient’s continued localized swelling after 50 days of treatment was considered to be closely related to postherpetic neuralgia. Lidocaine patches and gabapentin are effective in relieving the pain, and lidocaine patches are associated with skin reactions at the site of application, such as transient itching, erythema, and dermatitis. The side effects of Gabapentin are drowsiness and dizziness. It is advisable to visit a hospital for treatment of the above conditions, and the above medications should be used as prescribed by a doctor.