Bitter mouth and abdominal pain may be caused by reflux esophagitis, cholecystitis, cirrhosis of the liver and other diseases, which need to be treated under the guidance of the doctor, such as medication, surgery and so on. 1. Reflux esophagitis: stomach acid reflux to the mouth can have bitter mouth symptoms, can also be accompanied by abdominal discomfort; such patients need to pay attention to sleep elevated head of the bed, should not eat before going to bed, but also follow the doctor’s instructions to use omeprazole and other acid inhibitors, domperidone and other gastric dynamics of the drug treatment. 2. cholecystitis: acute attack need to fast, accompanied by severe pain can be used scopolamine pain, chronic cholecystitis patients, if recurrent attacks or internal medicine treatment is ineffective, recommended surgical treatment, acute cholecystitis with perforation also need surgical treatment. 3. Cirrhosis: patients with hepatitis B need to be treated with antiviral drugs such as entecavir, and can also use reduced glutathione and adenosylmethionine to protect the liver. It is recommended to go to the hospital when you have bitter mouth and abdominal pain, so that the doctor can make a judgment and clarify the cause of the disease.