Endocrine disorders may cause high blood pressure, as seen in pheochromocytoma, Cushing’s syndrome, and others. Treatment should be causative (surgical removal of the gland, treatment of hyperthyroidism, hormone replacement therapy, etc.), and simple blood pressure-lowering drugs may not be effective. 1. Surgical removal of glands: adenomas, pheochromocytomas, and Cushing’s syndrome in primary aldosteronism can lead to intractable hypertension, and the best treatment is generally surgical removal of adenomas or carcinomas, with adjunctive radiotherapy when necessary. 2. Treatment of hyperthyroidism: Hyperthyroidism causing sympathetic excitation may lead to hypertension, which can be treated with oral methimazole or propylthiouracil according to the cause of hyperthyroidism, and radiotherapy and surgery if necessary. 3. Hormone replacement therapy: congenital adrenocortical hyperplasia can cause hypertension due to some enzyme deficiencies, which requires glucocorticoid therapy. Menopausal women will have a series of endocrine hormone changes due to the decline of ovarian function, which may induce hypertension, and oral estrogen-progestin replacement therapy can be given. Endocrine disorders caused by high blood pressure to find a professional doctor in a timely manner, not blindly self-medication, so as not to delay the condition.