High aspartate aminotransferase suggests the possibility of acute myocardial infarction, hepatitis, dermatomyositis and other diseases, and the patient may have myocardial damage, liver cell damage, skeletal muscle cell damage and other hazards. 1. Myocardial injury: acute myocardial infarction leads to ischemia and hypoxia of myocardial cells, resulting in injury and even necrosis. Aspartate aminotransferase in myocardial cells, due to the damage of myocardial cells into the blood, the appearance of high aspartate aminotransferase, suggesting the occurrence of myocardial injury. 2. Liver cell damage: Hepatitis causes liver cell damage, aspartate aminotransferase in the mitochondria of liver cells enters the blood, and the presence of high aspartate aminotransferase suggests the danger of liver cell damage. 3. Skeletal muscle cell damage: dermatomyositis is an autoimmune disease that leads to skeletal muscle cell damage due to inflammation, and aspartate aminotransferase in skeletal muscle cells enters the bloodstream, and high aspartate aminotransferase in the blood suggests that skeletal muscle cell damage occurs. If high aspartate aminotransferase is diagnosed, early and standardized treatment is recommended to minimize the adverse effects of the disease.