Sore and swollen hands may be caused by strenuous exercise, muscle strain, rheumatoid arthritis and other reasons. 1. Strenuous exercise: it may be caused by doing push-ups, jumping exercises and other sports, so that there is a buildup of lactic acid in the hands, thus causing the phenomenon of soreness and swelling in the hands. 2. Muscle strain: it may be caused by trauma, degenerative diseases, malnutrition, etc. When the hand muscles are strained, due to local stimulation, the patient may experience hand pain and swelling. 3. Rheumatoid arthritis: it is a kind of allergic disease, one of the main manifestations of rheumatic fever, and the onset of the disease is closely related to group A streptococcus. Due to the stimulation of inflammation, patients with ankle, shoulder, wrist, elbow and other joints, can appear red, swelling, heat, pain phenomenon, which can induce hand pain and swelling. Sore and swollen hands can also be seen in other diseases, such as carpal tunnel syndrome, etc. It is recommended to go to the hospital in a timely manner, and follow the doctor’s instructions for treatment to avoid delaying the condition.