Spironolactone and furosemide can generally be taken at the same time, but you need to be under the guidance of a doctor, do not take the drugs without authorization. Spironolactone and furosemide have no contraindications, and taking them together will not affect their efficacy, so the two types of drugs can be taken at the same time. However, due to the individual differences in patients, patients should combine their own situation, ask the doctor’s guidance, follow the doctor’s instructions to take the drug, so as not to damage the health of the body. Spironolactone is a potassium-preserving diuretic, which can be used to treat hypertension, primary aldosteronism and other diseases. Some patients may experience hyperkalemia, nausea, vomiting, hyponatremia and other adverse reactions after taking spironolactone, which is contraindicated for patients with hyperkalemia. Furosemide also belongs to a kind of diuretic, which is used for the prevention of hypertension, acute renal failure and other diseases. Common adverse reactions are hypokalemia, shock, fatigue, muscle pain and so on. For furosemide components allergy need to be contraindicated. Pregnancy and allergy need to be taken with caution. Patients need to consult a doctor in time if symptoms of discomfort occur during the period of taking the drug.