Itchy palms and feet may be caused by diseases such as urticaria, tinea cruris, herpes sweat, or other diseases such as palmoplantar pustulosis. 1. urticaria: urticaria is mainly caused by exogenous or endogenous factors, patients will have angioedema, wind, itching and other symptoms, but also nausea, fever, vomiting and other systemic symptoms. 2. Tinea pedis: tinea pedis is mainly caused by fungal infections, the patient’s main rash for blisters, itching, scaling, cracking, vesicles and other symptoms, but also accompanied by skin damage, thickening of keratin, roughness, etc., usually accompanied by obvious itching symptoms. 3. Sweat herpes: the etiology of sweat herpes is not yet completely clear, considering local allergies, dermatophyte infections and mental and other factors. Patients mainly manifested in the palms of the hands, soles of the feet and other parts of the blisters, intense itching, and occasionally tingling, burning sensation and other symptoms. 4. Other: palmoplantar pustulosis, eczema and other diseases may also lead to itchy hands and feet. Patients with symptoms of itchy palms and feet should seek timely medical treatment as prescribed by the doctor.