When the patient’s feet abrasion blisters (blisters), the patient can be under the guidance of the doctor according to the size of the blisters and the accompanying performance, through the general treatment and topical medication to improve. 1. Smaller blisters: If the area of the blisters is small, generally less than 1cm in diameter, and there is no rupture, oozing and other phenomena, it is recommended that the patient try to wear loose and comfortable shoes and socks, and at the same time reduce the friction of walking and wait for the blisters to be absorbed by themselves. 2. Larger blisters without oozing: if the blisters are larger in size, generally larger than 1cm in diameter, but without oozing and rupture, patients can suction the blisters with the help of physicians, appropriate bandage, and reduce walking friction. 3. Larger blisters with oozing: If the area of blisters is relatively large, accompanied by oozing and rupture phenomenon, patients can be coated with iodophor, disinfectant alcohol and other disinfectants to moisturize the local clean and dry, in order to prevent the occurrence of infection. When the patient’s feet grinding up blisters, in serious cases, it is recommended to go to the regular hospital in a timely manner to deal with the guidance, try to avoid picking themselves.