Vomiting in HFMD, its possible cause is that HFMD directly involves the gastrointestinal mucosa, causing it to become inflamed; it may also be neurological involvement, thus manifesting the symptoms of vomiting. 1. Involvement of the gastrointestinal mucosa: HFMD is a contagious childhood disease caused by enterovirus infection, which can directly enter the digestive tract of children and cause damage, resulting in digestive reactions such as vomiting, abdominal pain, and loss of appetite. 2. Neurological involvement: HFMD can involve multiple systems and organs, such as the nervous system, digestive system, heart, lungs, skin, etc. When the nervous system is involved, it can cause intracranial hypertension or neurological dysfunction, which can lead to symptoms of vomiting. Most cases are critical when the nervous system is involved. Hand, foot and mouth disease vomiting, there may also be other causes, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.