The rate of progression of ischemic nephropathy mainly depends on the etiology, condition and treatment effect, and cannot be generalized.
Ischemic nephropathy is a chronic kidney disease caused by severe stenosis or obstruction of the main trunk of the renal artery or its main branches unilaterally or bilaterally leading to altered renal hemodynamics, which in turn results in a decrease in the glomerular filtration rate and renal hypoperfusion.
The causes of ischemic nephropathy include atherosclerosis, fibrous dysplasia, aortitis, hypertension-induced small-artery nephrosclerosis, cholesterol embolism, renal artery thrombosis, renal vasculitis, microangiopathy, and post-transplant renal artery stenosis.
If the degree of stenosis or obstruction is mild and reversible factors are corrected, such as renal artery stenosis recanalization, ischemic nephropathy may progress slowly after active treatment; if the condition is more severe and the treatment is not timely or the treatment is not effective, ischemic nephropathy may progress very quickly and develop into end-stage renal disease.
Patients with ischemic nephropathy are recommended to go to regular hospitals for timely consultation, improve the examination to clarify the cause of the disease, and give targeted treatment or therapy under the guidance of doctors.