Periapical inflammation needs to be treated by medication and surgery. 1. Medication: If there is obvious inflammation such as redness, swelling, heat and pain, or the inflammation spreads, you need to use antibiotics such as metronidazole, ceftriaxone, cefuroxime, and painkillers such as ibuprofen and acetaminophen under the guidance of the doctor, which can effectively relieve the symptoms. 2. Surgery: For patients in the acute stage, it is necessary to cooperate with the doctor to carry out open medullary drainage, and if there is an abscess, it is necessary to take incision and drainage of pus. After the acute phase is relieved, patients need to consider performing root canal therapy, apical curettage, apicoectomy and other surgical treatments. Generally, the prognosis of apical periodontitis is good after the above treatments, and most patients can retain the affected teeth. In conclusion, patients with apical periodontitis need to go to the hospital in time, cooperate with the doctor to actively carry out standardized treatment, and at the same time need to strengthen the management of daily life, regular follow-ups, and the use of medication should be in accordance with the doctor’s instructions.