In the case of transsphenoidal microsurgery, it is generally not dangerous to remove gauze after surgery. In the case of transfrontal craniotomy, it may be more dangerous to remove the gauze for a short period of time after surgery. Pituitary tumors are common neoplastic diseases of the nervous and endocrine systems. There are two broad types of surgical procedures for this disease, namely, transnasal butterfly microsurgery and transfrontal craniotomy. Therefore, determining whether or not it is dangerous to dial gauze after surgery for pituitary tumors needs to be based on the actual situation and cannot be generalized. In the case of transsphenoidal microsurgery, since the surgical area is not in the nose and the surgery is minimally invasive, it is generally not dangerous to remove the gauze, but it should be judged and operated by a professional surgeon and should not be removed on one’s own. In case of transfrontal craniotomy, since the operation area is in the brain and the scope is large, it is relatively dangerous to remove the gauze for a short period of time after the operation, and it is recommended that the patient consults with the doctor, who will judge when to remove the gauze and operate it. To summarize, after pituitary tumor surgery, patients need to actively cooperate with the doctor to pull out the gauze, and should not pull it out by themselves.