Lung cancer right middle finger pain is caused by paraneoplastic syndrome, which is an extrapulmonary manifestation of lung cancer. Lung cancer generally refers to malignant tumors of bronchial mucosa or glands in the lungs. The etiology of lung cancer is not yet clear, and it may be related to factors such as smoking, air pollution and ionizing radiation. Pain in the middle finger of the right hand is not necessarily related to lung cancer, and lung cancer patients usually do not have finger pain. Local growth of primary lung tumor may trigger symptoms including cough, blood in sputum, hemoptysis, and dyspnea. If the tumor invades adjacent organs, chest pain, hoarseness, pleural fluid, and Horner’s syndrome may occur. In addition, some patients may also develop hypertrophic pulmonary osteoarthropathy, pestle finger, pain in the middle finger of the right hand and so on. There are many symptoms of lung cancer, right middle finger pain may be paraneoplastic syndrome, but rheumatism and other possibilities can not be excluded. Patients are advised to go to regular hospitals and consult doctors in detail about related matters.