Dicyclanol generally does not cause elevated indirect bilirubin. Elevated indirect bilirubin needs to be considered in the presence of hematologic disorders, liver diseases, etc.
1. Blood system diseases: the most common disease that causes elevated indirect bilirubin level is hemolytic anemia, which is mainly due to the rapid destruction of red blood cells caused by a variety of reasons, and indirect bilirubin in the human body is usually mainly from the aging of the destroyed red blood cells, so when combined with hemolytic anemia, the level of indirect bilirubin will be elevated.
2. Liver disease: Physiologically, indirect bilirubin will combine with albumin and undergo a series of metabolic processes in the liver to transform into direct bilirubin, which further enters the intestinal and hepatic circulation.
However, in the presence of liver diseases such as cirrhosis, liver failure and alcoholic fatty liver disease, the liver’s ability to convert bilirubin into direct bilirubin decreases, resulting in elevated levels of indirect bilirubin.