Multiple metastases of lung cancer belong to tumors in advanced stage, which need standardized treatment under the guidance of clinicians, and commonly used treatment plans include local surgery, radiotherapy, chemotherapy, targeted therapy, immunotherapy and so on. 1. Local surgery: some metastatic tumors will cause obvious abnormalities in the surrounding tissues, causing pain and nerve function disorders, which can be relieved through local surgery. 2. Radiotherapy: generally for multiple metastatic tumors, extracorporeal radiotherapy can be carried out, and some metastatic tumors can be implanted with particles to control the development of the disease. 3. Chemotherapy: when there are multiple metastases, it is necessary to apply chemotherapeutic drugs periodically to control the disease, and the frequently applied drugs are cisplatin and so on. 4. Targeted therapy: for the type of lesions accompanied by gene mutation, you can choose to apply targeted drugs, such as gefitinib and so on. 5. Immunotherapy: Including PD-1 monoclonal antibodies such as pembrolizumab, nabulizumab, sindilizumab, and karelizumab. Besides, there are also monoclonal antibodies of PD-L1, including divalirumab and atalizumab, which have achieved certain results in the treatment of advanced lung cancer. People with multiple metastases of lung cancer need to seek medical treatment in time and carry out standardized treatment under the guidance of clinicians.