Itchy and swollen skin allergies may be caused by hives, contact dermatitis, eczema and other diseases, which should be clearly diagnosed and dealt with by general measures, medication and other means. 1. Hives: itchy and swollen skin allergies caused by hives, need to clarify the allergens, avoid re-exposure. Then oral loratadine, cetirizine and other antihistamines to stop the itching effect. 2. Contact dermatitis: itchy and swollen skin allergies may also be caused by contact dermatitis, patients should avoid re-exposure to irritants, sensitizers, can be treated with topical glucocorticosteroids, such as dexamethasone, hydrocortisone and so on. If necessary, oral antihistamines such as ebastine can be combined. 3. Eczema: Eczema can also lead to itchy, red and swollen skin, patients should pay attention to skin cleaning, to avoid damage to the skin barrier. It can be treated with topical glucocorticoids such as trimethoprim and mometasone furoate, which have an anti-inflammatory effect and can also relieve itching. Topical calcium-modulated phosphatase inhibitors such as pimecrolimus ointment and tacrolimus ointment can also be used. In addition, the causative factors need to be identified and avoided as much as possible. People with itchy and swollen skin allergies should seek medical examination and cooperate with doctors to standardize treatment. The above medications should be used in accordance with medical advice.