Under normal circumstances, the removal of wisdom teeth when anesthesia has no effect on the brain, disease conditions, if the injection of anesthesia after the occurrence of allergies, poisoning and other complications, there may be an effect on the brain, as follows. 1. Under normal circumstances: the removal of wisdom teeth usually choose local block anesthesia, commonly used drugs are lidocaine, ativan and so on, local anesthesia drugs act on the nerve trunk or its main branches nearby, blocking the incoming stimulation of the nerve endings, so as to produce anesthesia effect, generally have no effect on the brain. 2. In case of disease: (1) allergy: allergic to local anesthetic drugs will produce allergic symptoms, convulsions, coma, respiratory pulse arrest, etc., may have an effect on the brain. (2) poisoning: the amount of local anesthetic drug into the blood circulation per unit of time is too large, a drop in blood pressure, confusion and other symptoms, may have an impact on the brain. It is recommended to visit a regular medical institution to receive professional treatment.