High C-reactive protein CRP indicates the possible presence of septic infection, tissue necrosis, malignant tumor, and active rheumatic fever. C-reactive protein, widely found in serum and other body fluids, is an acute time-phase reactive protein synthesized by the liver, which can bind with bacterial and fungal nucleic acids, and has the functions of promoting phagocytosis and regulating immunity, etc. The normal reference value of CRP is <10mg/L, and the result varies according to different examination machines. CRP is commonly found in septic diseases, connective tissue diseases, acute rejection of organ transplantation, tissue necrosis such as myocardial infarction, severe trauma, burns, etc. CRP can identify certain diseases, such as bacterial infections CRP is often elevated, and non-bacterial is generally not elevated. CRP can be elevated during the active phase of rheumatic fever, but not during the stable phase. CRP can be elevated in organic diseases, but not in functional diseases, such as pregnant women with high CRP level is also normal. If CRP is found to be elevated, it is recommended to consult a doctor in time and receive standardized treatment after the cause of the disease is clarified, so as to avoid delaying the condition.