Reactive lymphoid hyperplasia of cervical lymph nodes with positive immunohistochemistry may be lymphoma, which needs to be diagnosed by combining the results of other tests such as imaging and pathological examination. There are many causes of reactive lymphoid hyperplasia in cervical lymph nodes, such as bacteria, virus, various foreign objects, which may stimulate the lymph node-related tissue cells and lead to hyperplasia, so the presence of hyperplasia is not necessarily lymphoma, but just can’t be ruled out as a possibility, and it needs to be combined with more comprehensive examinations. Immunohistochemistry can distinguish lymphoma from some other diseases, but the positive result can only indicate the possibility of lymphoma, and some normal cells may also have positive immunohistochemistry, so if you want to make a diagnosis, it is necessary to further combine with imaging and pathological examination. It is recommended to go to regular hospitals to avoid delaying the condition.