Callus on the palm of the foot is considered to be the possibility of callus, can be removed through general treatment, medication, physical therapy and other methods to improve the pain. 1. General treatment: it is recommended to change comfortable shoes and socks, keep the local dry and clean; you can also use hot water to soak the affected area, after the thickened parts of the corns are softened, the doctor will use a surgical blade to cut off the thickened corns. 2. Medication: commonly used salicylic acid ointment can be applied locally according to the size of the callus after the callus is flattened, and high concentration of urea cream can also be used to soften the keratin. 3. Physical therapy: the main treatment methods are liquid nitrogen freezing and carbon dioxide laser. If patients with callus caused by plantar deformity, you can choose some orthopedic insoles to improve the symptoms, or joint hand and foot surgeons to perform deformity correction surgery. It is recommended that patients with calluses on the soles of the feet and walking pain go to a regular hospital in a timely manner, under the guidance of the doctor to choose the appropriate treatment, the above drugs need to be used in accordance with the doctor’s instructions, not blindly used on their own, to avoid causing serious adverse reactions.