Redness and blistering of the skin may be caused by eczema, shingles, ringworm and other diseases. 1. Eczema: the basic causes of this disease include heredity, contact with allergens, hormone level disorders, trauma, autonomic nerve disorders and so on. In the acute stage, the lesions are characterized by papules and blisters on the basis of erythema, so the patients will have reddened skin with blisters. 2. Herpes zoster: This disease is caused by the reactivation of varicella-zoster virus after it is hosted in the human body. Typical symptoms are reddened blisters or papules on the chest, limbs, abdomen and other lesions, which may be accompanied by pain and burning sensation. 3. Ringworm: This disease is caused by fungal infections, such as Trichophyton rubrum, Trichophyton breakatum, and Trichophyton mustelii, etc. It can be transmitted by direct or indirect contact, and the lesions are mainly reddish blisters and pimples, which can occur on the trunk and arms. 4. other: in addition, also need to consider is hand, foot and mouth disease, genital herpes, syphilis, sweat herpes and other diseases caused. It is recommended that patients with reddened blisters go to the hospital, complete the relevant examinations and clarify the cause of the disease.