Frequent nighttime urination in girls can be a physiologic phenomenon caused by drinking too much water, or it can be caused by pregnancy, overactive bladder syndrome and diabetes. If it is caused by pathological factors, patients can follow the doctor’s instructions through oral medication and surgical methods of treatment. 1. Physiological phenomenon: girls who drink too much water at night or eat watermelon, pears and other fruits with a lot of water may cause frequent urination at night, which is a normal physiological phenomenon and does not require special treatment. 2. Pregnancy: After pregnancy, due to changes in estrogen and progesterone levels in the body, there may be frequent urination and other pregnancy reactions in early pregnancy. If accompanied by other symptoms such as fatigue, nausea, etc., it is recommended to go to the hospital for urinalysis and ultrasound for diagnosis. 3. Overactive Bladder Disorder: If the girls’ forced urinary muscles, bladder function is unstable or the bladder is too sensitive, it may lead to frequent night urination. You can take oral medication such as Solinacin tablets and Tolterodine tablets as prescribed by your doctor to improve the clinical symptoms. If the results are not good, you can also be treated with surgery such as cystoplasty and urinary diversion. 4. Diabetes: The typical symptoms of diabetes are excessive drinking, excessive urination, and excessive eating, so girls often get up at night to urinate may be caused by diabetes. Patients follow the doctor’s advice oral metformin, glimepiride and other hypoglycemic drugs for treatment. When girls have the symptom of frequent night urination, they should go to the hospital in time to clarify the cause of the disease, and under the guidance of the doctor reasonable treatment.