The wound is too deep not to heal, may be due to the wound site infection, the patient’s nutritional status is poor, suffering from diabetes and other chronic diseases caused by different reasons, treatment methods are different. 1. Wound site infection: wound site infection can lead to patients with wounds too deep, delayed healing symptoms, treatment should be wound debridement, regular dressing changes, drainage of purulent secretions, recombinant human epidermal growth factor gel and other drugs to promote wound healing, topical, and taking amoxicillin, oral cefixime and other antibiotics. 2. Malnutrition: malnutrition can also lead to symptoms of delayed wound healing, treatment should be given to patients to strengthen nutrition, supplemental albumin and other measures to promote healing. 3. Diabetes and other chronic diseases: diabetes and other chronic diseases can lead to delayed wound healing, or even can not heal, the need for strict control of blood glucose, taking amoxicillin, cefixime and other drugs to control infections, topical recombinant human epidermal growth factor gel and other drugs to promote healing. In addition to the above factors, other reasons can also lead to the symptoms of too deep wounds do not heal, it is recommended to consult a doctor to identify the cause and ask the doctor to deal with it.