Coughing at night may be caused by pneumonia or bronchitis, bronchial asthma, chronic obstructive pulmonary disease, etc., and its causes are different. 1. Pneumonia or bronchitis: due to bacterial or viral infection of the bronchial tubes or lungs leading to bronchitis or pneumonia, the vagus nerve excitability increases at night, which can cause a strong cough at night. Commonly used oral medications, such as: antibiotics for bacterial infections, such as amoxicillin, erythromycin and so on, for a severe dry cough, dextromethorphan and other treatments, accompanied by mucous sputum, can be given to aminoglutethimide and other treatments. At the same time, pay attention to rest, drink more water to promote sputum dilution discharge. 2. Bronchial asthma: due to airway hyperresponsiveness, large temperature difference between day and night, cold air stimulation at night leads to tracheal spasm, resulting in nocturnal cough. Glucocorticoids such as hydrocortisone and bronchodilators such as salbutamol aerosol can be used. At the same time, it is necessary to pay attention to keep warm and avoid inhaling irritating gases. 3. Chronic Obstructive Pulmonary Disease (COPD): The restriction of airflow may lead to coughing bouts in the morning or at night. It can be treated with inhaled bronchodilators such as salbutamol nebulized inhalation solution, terbutaline nebulizer, etc. In the acute infectious period, active anti-infective treatment is needed, and when accompanied by mucous sputum, active treatment such as bromhexine is given. Coughing at night may also be associated with other diseases, such as gastroesophageal reflux stimulation cough, cardiac insufficiency, etc. It is recommended to consult a doctor as soon as possible to clarify the cause of the disease, and choose symptomatic treatment under the guidance of the doctor. The above medications should be used under the guidance of a physician.