Sertraline Hydrochloride generally needs to be taken for 2 to 4 weeks to be effective, and relief of anxiety symptoms is determined by a combination of factors that vary from person to person. Sertraline hydrochloride as the mainstream selective 5-hydroxytryptamine reuptake inhibitors (SSRIs), the main role is to treat depressive disorders. For anxiety disorders efficacy has no advantage over other drugs, and clinically the preferred drugs for anxiety disorders are paroxetine, venlafaxine, duloxetine, escitalopram and so on. The elimination of anxiety symptoms is closely related to many factors such as severity, duration, cognitive function, co-morbidity, and family psychosocial. Simple generalized anxiety disorder generally requires 2 to 6 months of consolidation phase treatment and greater than 12 months of maintenance phase treatment. Patients with non-simple anxiety disorders are also affected by the treatment effects of other co-morbid psychiatric or somatic disorders. In addition, elimination of anxiety symptoms can be treated with a short course of benzodiazepines (lorazepam, etc.), or with buspirone and tandospirone. Psycho-cognitive-behavioral treatments are also important. Changing bad cognition and reconstructing cognition, as well as correct understanding of the disease, play an important role in eliminating anxiety symptoms. Specific treatment and medication should be carried out under the guidance of a doctor, do not make decisions on your own, in order to prevent adverse consequences.