The symptoms of appendicitis in women are the same as those in men, including metastatic right lower abdominal pain, gastrointestinal symptoms such as anorexia, nausea and diarrhea, and systemic symptoms such as fever and malaise. Women with acute appendicitis typically have metastatic right lower abdominal pain, i.e., abdominal pain starts in the upper abdomen, moves to the umbilicus over time, and then shifts to the right lower abdomen in about 6 to 8 hours, with pressure and rebound pain at the Mai’s point. The degree of abdominal pain is related to the type of appendicitis, e.g., mild vague pain in simple appendicitis, paroxysmal distension and severe pain in suppurative appendicitis. Appendicitis in women can also cause gastrointestinal symptoms such as anorexia, nausea, vomiting, diarrhea, and systemic symptoms of infection such as fever and malaise. It is important to note that appendicitis in women needs to be differentiated from right-sided gynecological diseases such as adnexitis and ectopic pregnancy.