In the second stage of femoral head necrosis, the change of cartilage surface of femoral head is not obvious, but there are mostly cystic changes under the cartilage surface, and the patients can show the pain feeling in the hip joint. The treatment is mainly based on the patient’s condition, including general treatment, physical therapy, medication and surgery. 1. General treatment: Because the femoral head has not collapsed in this period, patients are advised to avoid smoking and alcohol, avoid too much strenuous activities and weight-bearing walking, so as not to accelerate the damage of the femoral head, and use double crutches if necessary. 2. Physical therapy: local hot compresses, electrical stimulation and other physical therapy can be given to promote local blood circulation, which is conducive to the healing of ischemic necrosis of the bone. 3. Drug therapy: anticoagulant, vasodilator and lipid-lowering drugs, such as aspirin and Rosuvastatin, can be used in the clinic. 4. Surgical treatment: For those who fail to receive conservative treatment, surgical treatment such as drilling decompression surgery and bone grafting can be given. It is recommended that the patient should consult the doctor in time and complete all auxiliary examinations to clarify the condition, and the drugs should be used under the guidance of professional physicians.