Halometasone cream and dexamethasone cream can both be anti-inflammatory, anti-allergic, anti-itch, etc. The effect of the medication varies from person to person, so it is not possible to judge who has a better therapeutic effect. Halometasone cream is suitable for non-infectious inflammatory skin diseases that are effective in corticosteroid treatment, such as psoriasis, limited neurodermatitis, seborrheic dermatitis, contact dermatitis, atopic dermatitis, and numismatic dermatitis. Contraindications to the use of the drug include hypersensitivity to the product, bacterial, viral, fungal, syphilitic skin lesions, cutaneous tuberculosis, perioral dermatitis, rosacea, patients with acne vulgaris. Occasional burning sensation, itching and other symptoms of irritation at the site of application after use. Dexamethasone acetate cream is indicated for the treatment of contact dermatitis, neurodermatitis, seborrheic dermatitis, as well as limited pruritus, chronic eczema. Contraindications for use include those whose affected areas are broken, pus-filled or have obvious oozing, those with viral infections, and those who are allergic to the product. Long-term use can lead to skin atrophy, hyperpigmentation, capillary dilatation, secondary infections, and occasionally allergic reactions. The above two drugs are hormone drugs, all have anti-inflammatory, anti-allergy, anti-itch and other effects, the indications for the use of drugs are similar, at present can not be clearly judged which one of the drugs has a better therapeutic effect, mainly need to take into account the individual variability of the medication, the specific therapeutic effect varies from one person to another, the two drugs have their own suitable people. Specific medication should be carried out under the guidance of a specialist physician, not unauthorized use of medication.