Sudden confusion when walking may be caused by physiological factors, or it may be caused by transient amnesia, Alzheimer’s disease, and so on. 1. Physiological factors: If you are unfamiliar with the surrounding environment or are not familiar with the road conditions, you may suddenly lose your sense of direction. 2. Pathological factors (1) Transient amnesia: clinical manifestations of acute onset of short-term memory impairment, long-term memory retention, time and spatial orientation disorders can occur, but self-awareness and personality exists, there is no consciousness disorder, you can engage in more complex high-level cortical functional activities, lasting a few hours after the symptom can be relieved by itself, the etiology and pathogenesis of the cause is still not clear. (2) Alzheimer’s disease: Chronic progressive degenerative disease of the central nervous system leading to dementia, characterized by progressive memory impairment, cognitive dysfunction, personality changes and language disorders and other neuropsychiatric symptoms. It may be characterized by a sudden inability to recognize directions and people. If you have a sudden inability to recognize directions when walking, except for physiological factors, we recommend that you go to the hospital for further examination to confirm the diagnosis and treatment.