It is impossible to single out how many days to take duloxetine hydrochloride enteric-coated tablets to take effect, usually take the drug within 1~4 weeks the patient’s condition will be improved. Duloxetine hydrochloride enteric-coated tablets are psychiatric drugs used to treat depression. Patients need to swallow the medication, not chewing and crushing, so as not to affect the therapeutic effect of the drug. Generally speaking, the patient’s condition will gradually improve within 1 to 4 weeks after using the drug, but it is impossible to judge how many days after taking Duloxetine hydrochloride enteric-coated tablets will be effective, because each patient’s physical condition, the severity of the disease, and the treatment plan adopted and other factors are different, the effect of the drug will be different in time. Adverse reactions such as dizziness and headache may occur when taking the medication. Symptoms such as nausea, dizziness and abnormal sensations may occur after stopping the drug. Contraindicated in patients with known hypersensitivity to duloxetine or any of the inactive ingredients in the product. Treatment with the drug should also be avoided in patients with uncontrolled closed-angle glaucoma. For specific medications, patients are advised to follow their doctor’s instructions.