There is no universal two medicines for treating enlarged liver and spleen. From the perspective of traditional Chinese medicine, enlarged liver and spleen belong to the category of plaque (lump), which is generally related to depression and stagnation of liver qi, etc. Patients can use Chinese medicines such as Easy Pill, Anluo Huanfen Pill and Kaiyu Shuji Pill to regulate and treat the condition, and it is recommended to follow the doctor’s instructions for the use of the medicines. 1. Free Pill: composed of Atractylodes macrocephala, Radix Bupleurum Chinense, Radix Paeoniae Alba, Radix Angelicae Sinensis, etc., it has the efficacy of dredging the liver and strengthening the spleen, nourishing blood and regulating menstruation, and it can be used for treating symptoms such as loss of appetite, distension and pain in the chest, dizziness and dizziness due to the lack of comfort of the liver and qi. The adverse reactions and contraindications are not clear. 2. Anluo Huanfen Pill: It is a proprietary Chinese medicine composed of Dilong, Atractylodes macrocephala, Panax quinquefolius, leeches and silkworms, etc. It is effective in strengthening the spleen and nourishing the liver, cooling the blood and activating the blood circulation, and softening the firmness and dispersing the knots, and can be used in the treatment of pain in the chest and ribs, distension of the epigastric region (the abdomen), and fatigue of the mind and the body. Adverse effects are not known, and pregnant women are prohibited from using this medicine. 3. Kaiyu Shu Liver Pill: composed of Muxiang, Curcuma, Xiangshu, Wu Lingyi, Qingpi, etc. It has the efficacy of Kaiyu Shu Liver, Shunqi and relieve pain, and can be used to treat belching (belching), acid swallowing (swallowing the acid in the stomach that rushes upward to the oropharynx), chest and hypochondrium distension, abdominal pain, and other symptoms caused by liver depression and stagnation of qi. Adverse reactions are not clear, and it is contraindicated in pregnant women. Liver and spleen enlargement should be taken seriously, consult a doctor in time, and be treated with medication under the guidance of a doctor.