White spot disease is a symptom collectively, white spots on the skin need to clarify the cause of the disease, targeted treatment is the best treatment, such as vitiligo need to be given glucocorticoid drug treatment. 1. Vitiligo is a pigment deficiency disorder caused by immune system disorders and is associated with a variety of factors. Vitiligo in the progressive stage requires systematic use of glucocorticoid drugs to control the condition, such as oral methylprednisolone tablets, topical halometasone cream, clobetasol propionate cream and so on. 2. white chaff rash caused by white spots on the face, mostly in children, may be related to vitamin deficiencies, intestinal parasites and infections and other factors. Treatment can be oral vitamin B or multivitamin tablets to supplement vitamin B, and at the same time, topical 5% urea ointment to improve the symptoms. 3. Idiopathic pitting white spots are a manifestation of skin aging, usually seen in the elderly. This disease usually does not need treatment, with age can gradually increase, usually appropriate supplementation of vitamin E helps to delay skin aging. After the body white spots, it is best to check the Wood’s lamp and other skin examination to confirm whether it is vitiligo, and then use drugs under the guidance of the doctor.