Bivalent generally refers to the bivalent HPV vaccine, and women who are sexually active are recommended to have uterine cancer screening before the bivalent HPV vaccine. The bivalent HPV vaccine should be given between the ages of 9-45 years old before the vaccine is given. Women who are sexually active are recommended to have cervical cancer screening before vaccination, and those who are not sexually active can be exempted, subject to medical advice. The vaccine should not be given to patients who are in the midst of a disease flare-up, have a history of allergy to the vaccination, or are preparing for or during pregnancy. Women who are sexually active are advised to undergo cervical cancer screening before vaccination to rule out the possibility of cervical cancer. Women who have not had sexual intercourse do not need to undergo cervical cancer screening. Adverse reactions such as fever, headache, fatigue, cough, muscle pain, nausea, etc. may occur after vaccination, which can usually be relieved on their own. If breathing difficulties, hives or other serious adverse reactions occur, it is recommended to go to the hospital in time.