High total cholesterol requires lifestyle improvement and, if necessary, medication; high HDL requires no specific treatment. High total cholesterol often indicates an increased risk of atherosclerosis-induced cardiovascular and cerebrovascular diseases, so high total cholesterol levels require active intervention. Generally, we should start with improving our lifestyle, avoiding oily diet, quitting smoking and drinking, and maintaining sufficient rest; at the same time, we should increase the frequency of aerobic exercise, such as jogging, brisk walking, swimming, etc. In addition, we can also consider taking medication. In addition, you can also consider taking medication to control it. After consulting with a professional doctor, you can choose statins such as atorvastatin, cholesterol absorption inhibitors such as ezetimibe, and bile acid sequestrants such as kojic acid chelator. High-density cholesterol is a substance that facilitates the removal of cholesterol from peripheral tissues and prevents atherosclerosis, so its increased level is a good phenomenon that does not require intervention. It is recommended to consult a doctor for standardized diagnosis and treatment if necessary.