The blisters on the soles of the feet do not have to be punctured, if the blisters are relatively small, generally self-absorbing, for larger blisters, they need to be punctured treatment. 1. Do not need to poke: If the blisters on the soles of the feet are relatively small, you can use band-aids or gauze wraps to minimize local friction, generally self-absorbing, without poking. 2. Need to puncture: If the blister is relatively large, or there is a blood blister, will be accompanied by severe tingling and pain, you need to use a sterile syringe sterilized after poking, will be inside the liquid drainage, and the use of antiseptic water coated with the affected area, wrapped in plastic or adhesive tape. If not poked in time and rubbed repeatedly with shoes, it may break out and become infected. It is recommended that patients with blisters on the soles of their feet seek prompt medical attention and be treated accordingly under the guidance of a doctor.