The cost of syphilis treatment for stage I and II syphilis ranges from $100 to $1,000, while it is more expensive if it is stage III syphilis, and the price varies according to the condition. 1. If it is stage 1 and stage 2 syphilis, it can be cured in about one course of treatment, a course of treatment is 2 to 3 weeks, if you are not allergic to penicillin, you can inject penicillin intramuscularly, the whole process is about 100 yuan. 2. If you are allergic to penicillin, you can switch to ceftriaxone, which costs relatively more, about 200 to 300 yuan. 3. If it is stage III syphilis, there are more complications, which may require hospitalization and cost more. Complications are different, the cost is also different, this depends on the specific situation. It is recommended that the person concerned actively go to the hospital, the specific price can consult the local hospital, to the hospital’s offer shall prevail.