Infants waking up shaking their heads from side to side are considered to be caused by environmental factors or vitamin D deficiency rickets, eczema and other diseases. 1. Environmental factors: if the baby sleeps in an environment with an inappropriate temperature, or the blanket is too thick, the baby’s head may sweat more, which may irritate the scalp and cause discomfort, thus waking up shaking the head. 2. Vitamin D deficiency rickets: Vitamin D deficiency rickets is a calcium and phosphorus metabolism malfunction caused by vitamin D deficiency, the etiology of which is related to perinatal vitamin D insufficiency, insufficient sunlight, fast growth rate and other factors. Affected children will show signs of increased neural excitability, such as excessive sweating, irritability, and so on, thus appearing to wake up shaking the head around. 3. Eczema: babies waking up shaking their heads may also be caused by eczema, and local itching. The cause of eczema is not clear, with the body internal causes, external causes and psychosocial factors. The manifestation of polymorphic rash, often symmetrical distribution, the patient will be conscious of itching. Babies wake up shaking their heads, there may be other reasons, it is recommended to go to the hospital in time, improve the examination to clarify the cause, under the guidance of the doctor to give targeted treatment or treatment.