XindaYue, generic name vortioxetine hydrobromide tablets, and venlafaxine hydrochloride can be used for depression, it is impossible to tell who is more effective, the specific efficacy varies from person to person. Vortioxetine hydrobromide tablets are indicated for the treatment of depression in adults, and the mechanism of antidepressant action is not fully understood. The most common adverse reaction is nausea, which usually occurs in the first 2 weeks of starting treatment and is mild or moderate. Contraindications to use include patients who are hypersensitive to the product, and the combination with monoamine oxidase inhibitors (e.g., moclobemide, linezolid) should also be prohibited. Venlafaxine hydrochloride capsules are also indicated for the treatment of depression, and contraindications to use include patients who are allergic to the product, and patients who are taking monoamine oxidase inhibitors. Adverse drug reactions include nausea, anorexia, diarrhea, restlessness, weakness, headache, drowsiness, insomnia, dizziness, and tremor. Both drugs have a certain antidepressant effect, in view of the individual variability of users, resulting in these two drugs have the appropriate group of users, can not be judged as a whole who is more effective. The use of specific drugs should be under the guidance of specialists, not unauthorized use of drugs.