One pimple on the glans may be related to the causes of condyloma acuminatum, circumcision and glans penis, pearly pimples on the penis and so on. 1. Condyloma acuminatum: If there is unclean sex, when infected with human papillomavirus, one or more pimples may appear in the form of cauliflower pattern. 2. Foreskin glansitis: chronic inflammation due to long foreskin or prepuce can cause localized proliferation, appearing as a pimple. 3. Penile pearly pimples: mainly occur around the penile coronal groove, that is, the connection between the foreskin and the glans penis, the glans looks like wearing a “pearl necklace”, may be related to local infection, long-term stimulation and other factors. It is recommended that the people who have a pimple on the glans go to the hospital in time to clarify the cause of the disease, and carry out standardized treatment under the guidance of the doctor, so as not to delay the condition.