Toes with callus can be without treatment, medication, physical therapy, etc.. 1. No treatment: toes with callus is also called callus, which is long-term friction and pressure caused by the thickening of the skin stratum corneum, generally no self-awareness of the symptoms, if it is not particularly serious, do not need special treatment, these calluses can also have a certain protective effect on the skin. 2. medication: if you think the callus affects the beauty, you can choose the medication, more commonly used is salicylic acid paste, mainly after the callus is flattened, according to the size of the callus cut paste for pasting, you can also use a high concentration of urea cream and Vitamin A acid ointment coated. 3. Physical therapy: the callus can also be removed by liquid nitrogen freezing, carbon dioxide laser and other methods. The same disease, the patient’s physical condition is different, different stages of the disease, the treatment method is different, should be standardized under the guidance of the doctor.