Patients with mild liver fluke infection can be cured, and need timely scientific deworming and symptomatic treatment. However, some severe infected patients may be complicated by cirrhosis of the liver, bile duct cancer and other diseases, which cannot be cured. Hepatic schistosomiasis, also known as Schistosoma oryzae, gets its name because it can parasitize the liver and bile ducts of human body. When the human body is found to be infected with liver fluke, deworming treatment should be carried out in time. Mildly infected people usually have a good prognosis and can be cured. In some severe infections, fever, fatigue, abdominal pain, loss of appetite, dizziness, emaciation, edema, anemia and other symptoms, and in the advanced stage, it can cause cirrhosis of the liver, ascites, bile duct cancer and other serious complications, and the prognosis at this time is poor, difficult to cure. For liver fluke infection, it is necessary to give scientific deworming treatment, currently used in the treatment of liver fluke drugs are mainly praziquantel and albendazole, the specific use of drugs should follow the doctor’s instructions. For patients with fever, abdominal pain, anemia and other symptoms, can be given symptomatic treatment, daily patients should strengthen nutrition and rest. In order to avoid the infection of liver fluke, we should change the habit of eating raw or semi-raw fish and pay attention to the hygiene of diet and drinking water.