Hand peeling chili hot and painful, can be rinsed with water, local ice packs, can be treated with antihistamines, can help reduce the symptoms. 1. rinse with water: because chili pepper capsaicin can stimulate the nerve endings to cause pain and other discomforts, but can be dissolved in alcohol or acetic acid, so you can use white wine or vinegar to scrub the pain several times, and then rinse with water, can significantly reduce pain and other discomforts. 2. Ice: after rinsing with water, the pain persists, if necessary, you can use ice towels or ice water on the local ice, can effectively improve the symptoms. 3. Oral medication: symptoms continue to be unable to relieve, if necessary, under the guidance of a doctor to give oral medication, such as olopatadine hydrochloride, cetirizine hydrochloride, chlordiazepoxide, the drug has an anti-allergic effect, can reduce the symptoms of irritation. Hand peeling chili after the pain is more obvious, it is recommended to go to the hospital dermatology department, under the guidance of the doctor with medication.