Although severe hepatitis is more serious and has a higher mortality rate, it can be cured through timely and regular treatment. The treatment of severe hepatitis includes comprehensive treatment, treatment of complications, supportive therapy and other measures. Hepatitis is an inflammatory disease of the liver caused by microbial infection, immune response, drug action and other factors, hepatitis may develop into severe hepatitis if not treated in time. Patients with severe hepatitis are mainly characterized by nausea, vomiting, anorexia, abdominal discomfort, etc. Severe hepatitis may also have serious complications, such as upper gastrointestinal bleeding and abdominal infection. 1. Comprehensive treatment: maintain water-electrolyte balance, nutritional support, etc. 2. Complications treatment: for severe hepatitis-induced hepatic encephalopathy, upper gastrointestinal hemorrhage, abdominal infection, pulmonary infection, biliary infection, etc., give hemostasis, dehydration to reduce intracranial pressure, and anti-infection treatment. 3. Supportive treatment: Infusion of albumin, plasma, etc. to increase albumin level and supplement coagulation factors. 4. Other measures: some patients may consider taking hormone therapy, as well as artificial liver, liver transplantation and other therapeutic measures. Patients should be active in formal treatment, establish confidence in treatment, and carry out formal treatment under the guidance of doctors.