A 5-millimeter ground-glass nodule with burrs in the lung may be benign or malignant, and there is no way to determine its severity. A 5-mm ground glass nodule with burrs in the lungs cannot be determined to be benign or malignant purely from the external shape and size of the nodule. However, the possibility of malignant nodules is not completely ruled out, and it is best to have regular reviews for dynamic observation. If the 5-mm ground-glass nodule with burrs continues to grow, timely surgical resection should be considered to determine the severity of the nodule, and further pathological puncture examination should be performed. If the imaging examination of pulmonary ground glass nodule 5 mm with burr, must be in accordance with the medical advice to do a good job of follow-up observation, pay close attention to changes in the shape and size of the nodule, to rule out the possibility of malignant changes in a timely manner. Once malignant transformation occurs, it is recommended to cooperate with professional doctors to carry out treatment as soon as possible, including surgical resection treatment in the early stage, radiotherapy and chemotherapy in the later stage.