Vitamin A cream is generally not recommended for daily use, there is a course of treatment, the specific time of use should be decided by the physician in conjunction with the condition. Retinoic acid cream with all-trans retinoic acid as the main ingredient is mainly used as an adjunct to the treatment of flat warts, acne vulgaris, mucous membrane leukoplakia, erythema furfur, follicular keratosis and psoriasis. The drug is generally not recommended for long-term use, as well as not recommended for large areas of large quantities of use, and the specific use of drugs should be carried out under the guidance of specialists, not unauthorized use of drugs. The drug should be contraindicated for women in the first three months of pregnancy, breastfeeding women, people who need to use the drug in the eye area, as well as people who are allergic to the product. Adverse reactions of skin irritation (specifically burning, erythema and flaking) may occur during topical treatment, which generally indicates that the drug is working and most patients can adapt and tolerate it. If irritation persists, discontinue the drug or follow medical advice. It is recommended to seek medical advice when symptoms and discomfort occur, and to follow the doctor’s instructions.